Beyond Antibiotics: Integrative Strategies for Chronic Lyme Recovery

For many people, Lyme disease does not end when the antibiotic prescription does. Lingering symptoms such as fatigue, brain fog, joint pain, and immune dysfunction can persist long after standard treatment is complete. This is often referred to as chronic or persistent Lyme symptoms, and it is where an integrative, functional approach can make a meaningful difference.

Why Antibiotics Are Not Always Enough

Antibiotics play an important role in treating acute Lyme infections, but they do not always address the full picture. Lyme can disrupt the immune system, trigger chronic inflammation, impair detox pathways, and place a heavy burden on mitochondria, the cells responsible for energy production. When these systems remain compromised, symptoms may continue even after infection markers improve.

Functional medicine focuses on supporting the body’s ability to heal itself by addressing these downstream effects rather than relying on one intervention alone.

Ozone Therapy for Immune and Inflammatory Support

Ozone therapy is one tool used in integrative Lyme care. Ozone helps improve oxygen utilization at the cellular level and supports immune modulation. It can also assist in reducing inflammatory burden and supporting circulation.

In the context of Lyme recovery, ozone therapy may help the body better manage ongoing immune stress and improve overall resilience, especially when used as part of a broader treatment plan.

Peptides and Cellular Repair

Peptide therapy is another option often incorporated into Lyme recovery protocols. Peptides are short chains of amino acids that act as signaling molecules in the body. Certain peptides can support immune regulation, tissue repair, and mitochondrial function.

For individuals recovering from Lyme, peptides may help:

  • Support immune balance

  • Improve energy and recovery

  • Aid in tissue healing and inflammation control

Because peptides are selected based on individual needs, they are typically used in personalized protocols rather than one-size-fits-all approaches.

Detox Support for Lingering Toxin Burden

Lyme disease can place a significant burden on detox pathways. Inflammation, microbial byproducts, and environmental toxins can accumulate, making symptoms worse. Functional detox support focuses on enhancing the liver, gut, and lymphatic systems rather than aggressive cleansing.

This may include targeted supplementation, nutritional strategies, hydration support, and therapies designed to gently improve elimination without overwhelming the body.

NAD+ and Mitochondrial Recovery

Persistent fatigue is one of the most common Lyme-related complaints. NAD+ therapy supports mitochondrial function, helping cells produce energy more efficiently. By improving cellular energy and repair processes, NAD+ can play a role in restoring stamina, mental clarity, and overall vitality.

A Personalized Path Forward

At Rapha Wellness, chronic Lyme recovery is approached with individualized care. Through comprehensive diagnostics, we identify which systems need support and tailor integrative therapies accordingly. Healing from Lyme is rarely linear, but with the right strategies, progress is possible beyond antibiotics alone.

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